Certain mutations may have a significant impact on amino acid coding, which can modify what proteins are made, which can have a significant impact on cellular and organismal function. And what will happen if the base sequence of the coded codons is changed?
Because the active site’s form is no longer complementary to the substrate, the substrate may no longer be able to attach to it.
Because the genetic code is degenerate, if the codon GAA becomes the codon GAG, the amino acid glutamate will still be coded for. Silent mutations refer to ineffective mutations.
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